My taste in podcasts varies by what is actually going on in my life. Right now it is mostly startups (KickoffLabs) and Ruby.

Here are my current favorites:

The Lifestyle Business Podcast

Don’t let the name full you. These guys are seriously focused on solid business skills. I have only been listening to them for a month or two, but it is one the few podcasts I now listen to every week.

Two recent episodes stand out to me:

1. 9 Tough Truths About Running a Business and Changing Your Life.
2. The Tao of the Hustle

Mixergy

Mixergy might be the podcast I have been subscribed to the longest. What I really like about Mixergy is the mix interviews: Founders of big and small companies, VCs, and everyone in-between.

Recent favorites:

1. Curbly’s Founder Tells Me To Stop Ignoring Lifestyle Businesses – with Bruno Bornsztein
2. Molehill’s Founder: Aim For Lifestyle, Not A Jackpot – with Tom Rossi
3. How To Build A Profitable Lifestyle Web App, Even If You’re Not A Developer – with Dane Maxwell
4. Pitch Anything
5. Leadership Through Stories?! – with Derek Sivers

Note: Looks like the last two require a premium membership.

Ruby 5

Quick and concise updates on what is going in the Ruby world. Published twice a week and as you might guess, they are about 5 minutes long.

RailsCasts

Ryan Bates publishes a weekly screencast on Rails. If you do work with Rails (or want to) you absolutely must subscribe to this podcast.

Recent interesting episodes:

1. Pry with Rails
2. Understanding the Asset Pipeline

Others that I occasionaly listen to:

1. This Developers Life - Great developer stories.
2. The Changelog - This used to be one of my top 5, but it has fallen off the radar for me.
3. Ruby Rogues - Really good Ruby discussion on a single topic or two per week.
4. VimCasts - I continue to be shocked at what can be done in Vim.
5. Startups For the Rest of Us - If you are a developer and want to build your own startup, you can’t go wrong with this one.